Drug Interaction Checker

Save medications to your cabinet in the Pill Identifier — interactions are flagged automatically (WebMD-style). For a full personal check, use the cabinet feature.

Common major interactions we monitor

• warfarin + aspirin: Increased bleeding risk when combining anticoagulant and antiplatelet therapy.
• warfarin + ibuprofen: NSAIDs increase bleeding risk with warfarin.
• lisinopril + spironolactone: Combined ACE inhibitor and potassium-sparing diuretic may cause dangerous hyperkalemia.
• losartan + spironolactone: ARB plus spironolactone increases hyperkalemia risk.
• xanax + oxycodone: Benzodiazepine plus opioid increases respiratory depression risk.
• xanax + hydrocodone: Sedative combinations increase overdose and respiratory depression risk.
• sertraline + tramadol: Increased serotonin syndrome risk.
• fluoxetine + tramadol: SSRI plus tramadol increases serotonin syndrome risk.
• metoprolol + verapamil: Combined beta blocker and calcium channel blocker may cause bradycardia.
• zolpidem + xanax: Combining sedatives increases CNS depression.
• gabapentin + oxycodone: Increased sedation and respiratory depression risk.
• warfarin + ciprofloxacin: Antibiotic may increase warfarin effect and bleeding.