Ovarian cysts are fluid-filled sacs that develop on or inside an ovary and are very common among females of reproductive age1. Most ovarian cysts cause no symptoms and often go away on their own without treatment2. However, some cysts can cause pelvic pain, bloating, or complications such as rupture or ovarian torsion, which require medical attention12. Understanding the types, symptoms, causes, diagnosis, and treatment options is essential for effective management and prevention of ovarian cysts.
Types of Ovarian Cysts
Ovarian cysts are broadly classified into functional cysts and non-functional cysts3. Functional cysts are related to the menstrual cycle and include follicular cysts and corpus luteum cysts34. Follicular cysts form when the follicle, which normally releases an egg during ovulation, fails to rupture and instead fills with fluid, enlarging the ovary34. Corpus luteum cysts develop after ovulation when the corpus luteum, a structure that secretes progesterone to prepare the uterus for pregnancy, fills with fluid or mcv blood test results meaning and normal range34. Hemorrhagic corpus luteum cysts occur when blood accumulates inside the corpus luteum3.
Non-functional cysts include dermoid cysts (mature cystic teratomas), endometriomas, and theca lutein cysts35. Dermoid cysts contain various tissue types such as skin, hair, and sebaceous material because they arise from germ cells36. Endometriomas are cysts formed by ectopic endometrial tissue implanted on the ovaries, characteristic of endometriosis-stages-symptoms-and-treatment">endometriosis5. These cysts contain old blood, giving them a dark, chocolate-like appearance5. Theca lutein cysts are rare and usually associated with elevated human chorionic gonadotropin (hCG) levels, often seen in fertility treatments or molar pregnancies34.
| Cyst Type | Common Cause | Typical Treatment | Risk of Malignancy |
|---|---|---|---|
| Follicular cyst | Failed ovulation | Observation, hormonal therapy | Low |
| Corpus luteum cyst | Blood accumulation post-ovulation | Observation, surgery if large | Low |
| Theca lutein cyst | High hCG (pregnancy, fertility tx) | Usually resolves spontaneously | Very low |
| Endometrioma | Endometriosis | Surgery, hormonal therapy | Low to moderate |
| Dermoid cyst | Germ cell tumor | Surgical removal | Low |
| Sources:3456 | |||
Ovarian cysts can affect females of all ages, but the most common age range to be diagnosed is between 15 and 40 because many benign masses are associated with reproductive functions.
— Tiffany Stadnick, MD, HonorHealth Medical Staff12
Ovarian Cyst Symptoms
Most ovarian cysts are asymptomatic and are often discovered incidentally during routine pelvic exams or imaging37. Symptoms typically arise when cysts rupture, bleed, become large, or cause complications such as ovarian torsion37. The symptom profile varies depending on the cyst type.
Functional cysts usually resolve without symptoms3. When symptoms occur, they may include pelvic discomfort or irregular menstrual bleeding, especially with corpus luteum cysts38. Complications such as cyst rupture or ovarian torsion can cause sudden, severe pelvic pain that requires urgent medical attention37. Ovarian torsion happens when a cyst causes the ovary to twist, cutting off its blood supply and leading to ischemic pain37.
Endometriomas are associated with endometriosis, a condition where endometrial-like tissue grows outside the uterus causing chronic pelvic pain5. Pelvic pain related to endometriomas often begins before menstruation and can last several days into the menstrual period5. Pain during intercourse and menstrual irregularities may also be present52.
Dermoid cysts often remain asymptomatic but can cause abdominal or pelvic pain if they grow large or undergo torsion36. These cysts may also present as a firm, painless swelling in the lower abdomen9.
Although most ovarian cysts are benign, some cysts, especially those found after menopause or with complex features, may be malignant108. Symptoms suggestive of malignancy include persistent pelvic pain, abdominal bloating, urinary symptoms, and unexplained weight loss1011. Early detection significantly improves survival, with five-year survival rates exceeding 85% for early-stage ovarian cancer10.
Common Causes of Ovarian Cysts
Ovarian cysts form due to various mechanisms, most commonly related to the menstrual cycle3. Functional cysts arise from failure of ovulation, where the follicle does not rupture to release the egg, leading to fluid accumulation34. Hormonal imbalances disrupting the menstrual cycle can prevent ovulation and contribute to cyst formation3. Elevated hCG levels, as seen in molar pregnancies or fertility treatments, can cause theca lutein cysts3. Endometriosis is another distinct cause, where ectopic endometrial tissue implants on the ovaries forming endometriomas53.
Several factors increase the likelihood of developing ovarian cysts:
- Hormonal imbalances affecting ovulation32
- Use of fertility treatments involving hormone stimulation34
- Endometriosis53
- Pregnancy, especially molar pregnancies with high hCG levels3
- Previous history of ovarian cysts212
- Age, with cysts more common in reproductive years but malignancy risk higher post-menopause1012
Diagnosing Ovarian Cysts
Ovarian cysts are often found incidentally during routine pelvic examinations or imaging studies37. When symptoms suggestive of cysts occur, a thorough history and physical examination are essential313. Pelvic examination may detect adnexal masses suggestive of cysts3. Ultrasound is the primary diagnostic tool used to characterize cysts, distinguishing simple from complex cysts and assessing size and features313. Doppler ultrasound evaluates ovarian blood flow, which is crucial in suspected ovarian torsion37. Advanced imaging such as MRI or CT is reserved for complex cysts or when malignancy is suspected313. Laboratory tests may include hormone levels and tumor markers to aid diagnosis313.
Ovarian Cyst Treatment Options
Treatment aims to resolve cysts, relieve symptoms, and address any underlying conditions3. Most functional cysts regress spontaneously within a few menstrual cycles and require only observation312. Hormonal contraceptives reduce the formation of new functional cysts by suppressing ovulation but do not shrink existing cysts38. Pain management with nonsteroidal anti-inflammatory drugs (NSAIDs) is common for symptomatic relief32.
Surgery is indicated for cysts that are persistent, large (greater than 10 cm), symptomatic, or suspicious for malignancy313. Minimally invasive laparoscopic cystectomy is the preferred surgical approach for benign cyst removal314. In some cases, oophorectomy (removal of the ovary) may be necessary13.
| Treatment Option | Indication | Notes |
|---|---|---|
| Observation | Small, asymptomatic functional cysts | Most resolve in 8–12 weeks312 |
| Hormonal contraceptives | Prevention of new functional cysts | Do not shrink existing cysts38 |
| NSAIDs | Symptomatic pain relief | Commonly used32 |
| Laparoscopic cystectomy | Persistent, large, symptomatic cysts | Minimally invasive preferred314 |
| Oophorectomy | Suspicious or malignant cysts | May be required13 |
“Ovarian cysts are generally benign and resolve with time. The management of an ovarian cyst is a shared decision-making process that involves two experts coming to the table — you and your doctor — to create a treatment plan that is specifically made for you.”
— Tiffany Stadnick, MD, HonorHealth Medical Staff12
Preventing Ovarian Cysts
Complete prevention of ovarian cysts is not guaranteed in menstruating individuals3. However, hormonal contraceptives reduce the incidence of functional ovarian cysts by suppressing ovulation38. By preventing follicular development, contraceptives lower the chance of cyst formation3. Maintaining hormonal balance and managing underlying conditions like endometriosis may also help reduce risk53.
If a cyst is not causing pain, watchful waiting can be considered with your OB/Gyn, depending on the size of the ovarian cyst and your age at presentation. Generally, there are certain size criteria that warrant closer observation. Many ovarian cysts will resolve on their own after one or two menstrual cycles.
— Tiffany Stadnick, MD, HonorHealth Medical Staff12
Managing Ovarian Cysts
Management of ovarian cysts depends on cyst type, size, symptoms, and patient factors such as age and menopausal status312. Many cysts resolve spontaneously without intervention, especially in women of reproductive age12. Regular monitoring with ultrasound is often recommended for asymptomatic cysts37. Symptomatic cysts may require pain management or hormonal therapy32. Surgical intervention is reserved for cysts that do not resolve, cause significant symptoms, or have features suspicious for malignancy313.
Lifestyle measures such as maintaining a balanced diet, regular exercise, and heat therapy may help alleviate symptoms15. Prompt medical evaluation is necessary if sudden severe pelvic pain, fever, vomiting, or signs of shock occur, as these may indicate cyst rupture or torsion17.
